Chronic fatigue is a complex medical condition characterized by extreme and persistent tiredness, fatigue, or exhaustion that is not improved by rest and is not directly caused by other medical conditions. Some key features of chronic fatigue include:
Some common symptoms associated with chronic fatigue in addition to persistent exhaustion include:
What causes chronic fatigue? While the exact mechanisms are unclear, some suspected factors include:
Chronic fatigue often follows a viral illness (like mononucleosis). But research suggests biological abnormalities in the body's immune, neurological, hormonal, cardiovascular, and energy production systems likely also play a role. Genetic factors may predispose some people. In many cases, the cause remains unknown - there is still much we don't understand.
Diagnosing chronic fatigue involves ruling out other potential causes through history, physical exam, and targeted medical testing based on the symptoms and presentation. There are no definitive laboratory tests. Treatment focuses on symptom management, with cognitive behavioral therapy and graded exercise providing modest benefits for some patients.
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